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recombinant rat trka fc  (R&D Systems)


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    Structured Review

    R&D Systems recombinant rat trka fc
    Recombinant Rat Trka Fc, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 6 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+rat+trka+fc+chimera/Recombinant+Rat+TrkA+Fc+Chimera+Protein%2C+CF/pm31851405-137-10-13
    Average 90 stars, based on 6 article reviews
    recombinant rat trka fc - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    Recombinant:

    Article Title: Neurotrophic actions initiated by proNGF in adult sensory neurons may require peri-somatic glia to drive local cleavage to NGF
    Article Snippet: Purified NGF from mouse submaxillary glands was purchased from Sigma (St Louis, MO, USA; Cat. No. N6009). .. Recombinant rat TrkA/Fc chimera (4 ng/ml) was purchased from R&D Systems (Minneapolis, MN, USA; Cat. No. 1056-TK) and functional blocking anti-mouse p75 polyclonal antibody (1:400) from Chemicon International (Temecula, CA, USA; Cat. No. AB1554, lot 0606031680). .. LY294002 (50 μM), wortmannin (10 μM), U0126 (20 μM), PD98059 (50 μM), SU6656 (2 μM), and K252a (100 nM) were all purchased from Biomol Research Laboratories (Plymouth Meeting, PA, USA).

    Article Title: Suppression of p75 Neurotrophin Receptor Surface Expression with Intrabodies Influences Bcl-xL mRNA Expression and Neurite Outgrowth in PC12 Cells
    Article Snippet: The binding kinetics of scFvs was measured by surface plasmon resonance spectroscopy using a Biacore2000 and a CM5 chip (Biacore, Sweden). .. The antigen p75NTRex-Fc and the recombinant rat TrkA/Fc chimera (rat TrkAex-Fc, R&D systems, USA) were separately coupled on to the chip via amine coupling according to the manufacturer's instructions. ..

    Article Title: Co-cultures provide a new tool to probe communication between adult sensory neurons and urothelium.
    Article Snippet: .. Some cultures were treated with NGF (10 ng/ml) (Sigma), K252a (100 nM) (Biomol Research Laboratories, Plymouth Meeting, Pennsylvania) or recombinant rat TrkA/Fc chimera (4 ng/ml) (R&D Systems®). ..

    Article Title: Co-cultures provide a new tool to probe communication between adult sensory neurons and urothelium
    Article Snippet: .. Some cultures were treated with nerve growth factor (NGF; 10 ng/ml, Sigma), K252a (100nM, Biomol Research Laboratories, Plymouth Meeting, PA) or recombinant rat TrkA/Fc chimera (4 ng/ml, R&D Systems, Minneapolis, MN); these concentrations are effective in cultures of adult rodent neurons 15 . ..

    Article Title: A local anesthetic, ropivacaine, suppresses activated microglia via a nerve growth factor-dependent mechanism and astrocytes via a nerve growth factor-independent mechanism in neuropathic pain
    Article Snippet: .. To block the actions of NGF, a recombinant rat TrkA-Fc chimera (Recombinant Rat TrkA-Fc Chimera; R&D Systems, Minneapolis, MN) was epidurally injected at 1 h before ropivacaine administration from days 7 to 9 after CCI. .. As a control, a recombinant human IgG 1 -Fc protein (R&D Systems) or saline was injected.

    Article Title: Selective and differential interactions of BNN27, a novel C17-spiroepoxy steroid derivative, with TrkA receptors, regulating neuronal survival and differentiation.
    Article Snippet: .. The recombinant Rat TrkA/Fc chimera containing the rat TrkA extracellular domain was purchased by R&D Systems, Inc. NGF (NGF 2.5S, mouse) was purchased by Millipore. .. D2O 99.9% from Euriso-Top was used for the PBS buffer.

    Functional Assay:

    Article Title: Neurotrophic actions initiated by proNGF in adult sensory neurons may require peri-somatic glia to drive local cleavage to NGF
    Article Snippet: Purified NGF from mouse submaxillary glands was purchased from Sigma (St Louis, MO, USA; Cat. No. N6009). .. Recombinant rat TrkA/Fc chimera (4 ng/ml) was purchased from R&D Systems (Minneapolis, MN, USA; Cat. No. 1056-TK) and functional blocking anti-mouse p75 polyclonal antibody (1:400) from Chemicon International (Temecula, CA, USA; Cat. No. AB1554, lot 0606031680). .. LY294002 (50 μM), wortmannin (10 μM), U0126 (20 μM), PD98059 (50 μM), SU6656 (2 μM), and K252a (100 nM) were all purchased from Biomol Research Laboratories (Plymouth Meeting, PA, USA).

    Blocking Assay:

    Article Title: Neurotrophic actions initiated by proNGF in adult sensory neurons may require peri-somatic glia to drive local cleavage to NGF
    Article Snippet: Purified NGF from mouse submaxillary glands was purchased from Sigma (St Louis, MO, USA; Cat. No. N6009). .. Recombinant rat TrkA/Fc chimera (4 ng/ml) was purchased from R&D Systems (Minneapolis, MN, USA; Cat. No. 1056-TK) and functional blocking anti-mouse p75 polyclonal antibody (1:400) from Chemicon International (Temecula, CA, USA; Cat. No. AB1554, lot 0606031680). .. LY294002 (50 μM), wortmannin (10 μM), U0126 (20 μM), PD98059 (50 μM), SU6656 (2 μM), and K252a (100 nM) were all purchased from Biomol Research Laboratories (Plymouth Meeting, PA, USA).

    Article Title: A local anesthetic, ropivacaine, suppresses activated microglia via a nerve growth factor-dependent mechanism and astrocytes via a nerve growth factor-independent mechanism in neuropathic pain
    Article Snippet: .. To block the actions of NGF, a recombinant rat TrkA-Fc chimera (Recombinant Rat TrkA-Fc Chimera; R&D Systems, Minneapolis, MN) was epidurally injected at 1 h before ropivacaine administration from days 7 to 9 after CCI. .. As a control, a recombinant human IgG 1 -Fc protein (R&D Systems) or saline was injected.

    Injection:

    Article Title: A local anesthetic, ropivacaine, suppresses activated microglia via a nerve growth factor-dependent mechanism and astrocytes via a nerve growth factor-independent mechanism in neuropathic pain
    Article Snippet: .. To block the actions of NGF, a recombinant rat TrkA-Fc chimera (Recombinant Rat TrkA-Fc Chimera; R&D Systems, Minneapolis, MN) was epidurally injected at 1 h before ropivacaine administration from days 7 to 9 after CCI. .. As a control, a recombinant human IgG 1 -Fc protein (R&D Systems) or saline was injected.



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